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Anti-HER2 Antibody ErbB2
Catalog #: 188-10075
Mouse anti-Human HER2 Antibody ErbB2
Product Description
Specifications
| Size | 20 µg, 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P04626 |
| Gene Id | 2064 |
| Gene Symbols | ERBB2,HER2,MLN19,NEU,NGL |
| Protein Name / Synonyms | Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340) |
| Immunogen | Recombinant human protein was used as the immunogen for this HER2 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 0.2 mg/ml in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | FACS: 0.5-1ug/million cells in 0.1ml IF: 1-2ug/ml IHC (FFPE): 0.5-1ug/ml for 30 min at Room Temp (1) |
| Domain / Region / Terminus | Cell surface |
| Research Area | Angiogenesis, Cardiovascular Disease, Cancer, HER/ErbB Signaling |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
This mAb is specific to HER2 / ErbB2 and shows minimal cross-reaction with other members of the family. HER2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. HER2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Storage
Store the HER2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.