Anti-HMG2 (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P52926
Gene Id	8091
Gene Symbols	HMGA2
Protein Name / Synonyms	HMG2 (Ascites)
Clonality	Monoclonal
Preparation	This HMG2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from human HMG2.
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specificity

Predicted Reactivity

Mouse

Other Names

HMGA2; HMGIC; High mobility group protein HMGI-C; High mobility group AT-hook protein 2

NCBI Accession #

NP_003474.1;NP_003475.1

Other Accession #

P52927; NP_003474.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

11832

Recommended Dilutions

WB: 1:500-8000

HMG2 Antibody (Cat# 102-10308) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HMG2 antibody detected the HMG2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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