RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

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770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-HMGB2 Antibody

Catalog #: 144-64905

HMGB2 pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
P26583
Gene Id
3148
Gene Symbols
HMGB2
Protein Name / Synonyms
HMGB2, HMG2, high mobility group box 2
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, pH7.3
Recommended ApplicationsWestern Blotting, IHC, IF
Research AreaInflammation
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:100; IF 1:50 - 1:100

Format

Calculated MW
24kDa
Observed MW
30kDa

Immunogen

Recombinant protein of human HMGB2.

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.