Anti-HPSE2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8WWQ2
Gene Id	60495
Gene Symbols	HPSE2
Protein Name / Synonyms	HPSE2 (C-term)
Clonality	Polyclonal
Preparation	This HPSE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the C-terminal region of human HPSE2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.

Specificity

Predicted Reactivity

Mouse

Other Names

HPSE2; HPA2; Inactive heparanase-2

NCBI Accession #

NP_001159716.1;NP_001159717.1;NP_001159718.1;NP_068600.4

Other Accession #

B2RY83; NP_001159717.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

66596

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of lysates from HeLa, Jurkat cell line (from left to right), using HPSE2 Antibody (C-term)(Cat# 102-11814). 102-11814 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
	HPSE2 Antibody (C-term) (Cat# 102-11814)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HPSE2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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