Anti-HTRA2 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	O43464
Gene Id	27429
Gene Symbols	HTRA2
Protein Name / Synonyms	HTRA2, MGCA8, OMI, PARK13, PRSS25, HtrA serine peptidase 2
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IHC, IP
Research Area	Apoptosis, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IP 1:50 - 1:100

Format

Calculated MW

38kDa/39kDa/46kDa/48kDa

Observed MW

Refer to figures

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 334-458 of human HTRA2 (NP_037379.1).

Modification

Unmodified

Storage

-20°C

Images

Immunoprecipitation analysis of 200ug extracts of MCF-7 cells, using 3 ug HTRA2 antibody (144-60834). Western blot was performed from the immunoprecipitate using HTRA2 antibody (144-60834) at a dilition of 1:1000.
Immunoprecipitation - HTRA2 Polyclonal Antibody (144-60834)

Expiration:

12 months from the date of shipment when stored properly.

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