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Anti-Human CD117 Antibody, RayBright® Violet 450
Catalog #: 136-08075
Human CD117 Antibody [clone: BA7.3C.9], monoclonal mouse IgG2a. Validated for flow cytometry.
Product Description
Specifications
| Size | 25 tests, 100 tests |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P10721 |
| Gene Id | 3815 |
| Gene Symbols | KIT, SCFR |
| Protein Name / Synonyms | Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117) |
| Clonality | Monoclonal |
| Clone | BA7.3C.9 |
| Conjugation | RayBright® Violet 450 |
| Preparation | The antibody was purified by affinity chromatography. |
| Isotype | IgG2a |
| Format | Liquid |
| Concentration (lot specific) | 5 μl/test |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease, Cancer, Inflammation |
| Excitation Laser | Violet Laser, 407 nm |
| Maximum Emission Wavelength | 454 nm, replace Pacific Blue™ |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
CD117 is a receptor for stem cell factor and is expressed on pluripotent hematopoietic progenitor cells mast cells, and acute myeloid leukemia cells. When CD117 and its ligand bind, autophosphorylation and dimerization are induced. This activates intracellular signalling pathways essential for the growth and differentiation of hematopoietic stem cells.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.