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Anti-Human CD183 Antibody, Biotinylated
Catalog #: 136-01078
Biotinylated Human CD183 Antibody [clone: 1C6 [LS77-1C6]], monoclonal Mouse IgG1. Validated for flow cytometry.
Product Description
Specifications
| Size | 100 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Protein Name / Synonyms | CXCR3, IP-10 (Mig), GPR9, CKR-L2 |
| Clonality | Monoclonal |
| Clone | 1C6 [LS77-1C6] |
| Conjugation | Biotin |
| Preparation | The antibody was purified by affinity chromatography. |
| Isotype | IgG1 |
| Format | Liquid |
| Concentration (lot specific) | 0.5 mg/ml |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
CD183 is a seven-pass transmembrane chemokine receptor that binds CXCL9, CXCL10, and CXCL11. CD183 is expressed in large quantities by T cells, as well as NK cells, dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CD183 is important in the imflammatory response for many autoimmune diseases such as Crohn's disease, rhumatoid arthritis, and multiple sclerosis.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. We suggest use ≤ 0.5 µg per million cells in 100 µl volume of staining buffer. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Stored at 2 °C - 8 °C, protected from prolonged light exposure. DO NOT FREEZE.