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Anti-I kappa B-alpha (Phospho-Tyr305) Antibody
Catalog #: 102-26362
Rabbit Anti-I kappa B-alpha (Phospho-Tyr305) Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P25963 |
| Gene Id | 4792 |
| Gene Symbols | NFKBIA |
| Protein Name / Synonyms | NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI |
| Clonality | Polyclonal |
| Recommended Applications | Western Blotting, IHC |
| Research Area | Cancer, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Other Information
Antigen Type
synthetic peptide
Images
WB (1:1000)
Western blot analysis of extracts from COS7 cells, treated with nocodazole (1ug/ml, 16hours), using I?B-? (Phospho-Tyr305) antibody.
IHC (1:50~100)
Immunohistochemistry analysis of paraffin-embedded human lymph node tissue using I?B-? (Phospho-Tyr305) antibody.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.