RayBiotech

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ISO 13485:2016 cGMP

Anti-IDS Antibody

Catalog #: 144-01857

IDS Polyclonal Antibody

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
P22304
Gene Id
3423
Gene Symbols
IDS
Protein Name / Synonyms
IDS, MPS2, SIDS, iduronate 2-sulfatase
ClonalityPolyclonal
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
34kDa/38kDa/61kDa
Observed MW
76kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 34-290 of human IDS (NP_006114.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using IDS antibody (144-01857) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
Western blot - IDS antibody (144-01857)

Expiration:
12 months from the date of shipment when stored properly.