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Anti-IGF-1 Antibody, Sodium Azide Free
Catalog #: 188-10467-SAF
Mouse anti-Human/Mouse/Rat/Rabbit IGF-1 Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P05019 |
| Gene Id | 3479 |
| Gene Symbols | IGF1,IBP1 |
| Protein Name / Synonyms | Insulin-like growth factor I (IGF-I) (Mechano growth factor) (MGF) (Somatomedin-C) |
| Immunogen | Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | Flow Cytometry: 0.5-1ug/million cells in 0.1ml Immunofluorescence: 1-2ug/ml Functional Activity: In-vitro neutralization of biological activity of IGF-1 (Order SAF formulation) |
| Domain / Region / Terminus | Cytoplasmic (secreted) |
| Research Area | Cancer, Inflammation, IGF Signaling |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Storage
Store the IGF-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.