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ISO 13485:2016 cGMP
Anti-IgM Antibody Cocktail
Catalog #: 188-10474-IHC
Mouse anti-Human IgM Antibody Cocktail [IHC only]
Product Description
Specifications
| Size | 7 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P01871 |
| Gene Id | 3507 |
| Gene Symbols | IGHM |
| Protein Name / Synonyms | Immunoglobulin heavy constant mu (Ig mu chain C region) (Ig mu chain C region GAL) (Ig mu chain C region OU) |
| Immunogen | Recombinant heavy chain of human IgM (IM260 IM373 & ICO-30) was used as the immunogen for the Anti-IgM antibody cocktail. |
| Isotype | Kappa, IgG2b, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only* |
| Recommended Applications | Prediluted format : incubate for 30 min at RT (2) |
| Domain / Region / Terminus | Cytoplasm, cell surface and secreted |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Storage
Store the Anti-IgM antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.