Anti-IL10 (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P22301
Gene Id	3586
Gene Symbols	IL10
Protein Name / Synonyms	IL10(Ascites)
Clonality	Monoclonal
Preparation	This IL10 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 27-53 amino acids from human IL10.
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Inflammation, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq].

Specificity

Predicted Reactivity

EBV, Monkey

Other Names

IL10; Interleukin-10; Cytokine synthesis inhibitory factor

NCBI Accession #

NP_000563.1

Other Accession #

P79338; P03180; NP_000563.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

20517

Recommended Dilutions

WB: 1:100-400

IL10 Antibody (Cat# 102-10325) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the IL10 antibody detected the IL10 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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