3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-IL15RA (Center) Antibody
Catalog #: 102-14021
Rabbit Anti-Human IL15RA (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q13261 |
| Gene Id | 3601 |
| Gene Symbols | IL15RA |
| Protein Name / Synonyms | IL15RA (Center) |
| Clonality | Polyclonal |
| Preparation | This IL15RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-106 amino acids from the Central region of human IL15RA. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Specificity
Other Names
IL15RA; Interleukin-15 receptor subunit alpha; CD_antigen=CD215; Soluble interleukin-15 receptor subunit alpha
NCBI Accession #
NP_001230468.1;NP_001243694.1;NP_002180.1;NP_751950.2
Other Accession #
NP_751950.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
28233
Recommended Dilutions
WB: 1:1000
 | IL15RA Antibody (Center)(Cat# 102-14021) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the IL15RA antibody detected the IL15RA protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.