Anti-IL17A (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q16552
Gene Id	3605
Gene Symbols	IL17A
Protein Name / Synonyms	IL17A (Center)
Clonality	Polyclonal
Preparation	This IL17A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-87 amino acids from the Central region of human IL17A.
Concentration (lot specific)	0.470 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Specificity

Predicted Reactivity

Bovine

Other Names

IL17A; CTLA8; IL17; Interleukin-17A; Cytotoxic T-lymphocyte-associated antigen 8

NCBI Accession #

NP_002181.1

Other Accession #

Q687Y7; NP_002181.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

17504

Recommended Dilutions

WB: 1:1000

Western blot analysis of IL17A (arrow) using rabbit polyclonal IL17A Antibody (Center) (Cat# 102-11791). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IL17A gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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