RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-IL1A Antibody

Catalog #: 144-02170

IL1A Polyclonal Antibody

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
P01583
Gene Id
3552
Gene Symbols
IL1A
Protein Name / Synonyms
IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin-1 alpha
ClonalityPolyclonal
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting
Research AreaAngiogenesis, Cancer, Inflammation
Shipping TypeBlue ice
Storage-20°C

Description

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
30kDa
Observed MW
34kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 112-271 of human IL1A (NP_000566.3).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using IL1A antibody (144-02170) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Western blot - IL1A antibody (144-02170)

Expiration:
12 months from the date of shipment when stored properly.