Anti-IL1RAP Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q9NPH3
Gene Id	3556
Gene Symbols	IL1RAP
Protein Name / Synonyms	IL1RAP, C3orf13, IL-1RAcP, IL1R3, interleukin-1 receptor accessory protein
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting
Research Area	Inflammation, Ras/Rap Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

Background

Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW

39kDa/41kDa/65kDa/78kDa

Observed MW

90kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 21-356 of human IL1RAP (NP_001161402.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using IL1RAP antibody (144-05349) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
Western blot - IL1RAP antibody (144-05349)

Expiration:

12 months from the date of shipment when stored properly.

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