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Anti-INS Antibody
Catalog #: 102-20046
Mouse Anti-INS Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P01308|NP_001172027.1|NP_001172026.1 |
| Gene Id | 3630 |
| Gene Symbols | INS |
| Protein Name / Synonyms | Insulin, Insulin B chain, Insulin A chain, INS |
| Clonality | Monoclonal |
| Clone | 396CT20.4.4 |
| Isotype | IgM |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Other Information
Antigen Type
Synthetic Peptide
Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
11981
Expiration:
12 months from the date of shipment when stored properly.