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Anti-Interferon alpha Antibody, Sodium Azide Free
Catalog #: 188-10462-SAF
Mouse anti-Human Interferon alpha Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P01562 |
| Gene Id | 3439|3447 |
| Gene Symbols | IFNA1,IFNA13 |
| Protein Name / Synonyms | Interferon alpha-1/13 (IFN-alpha-1/13) (Interferon alpha-D) (LeIF D) |
| Immunogen | Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | ELISA: order BSA/azide-free format for coating |
| Domain / Region / Terminus | Cytoplasmic, extracellular (secreted) |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
Storage
Store the Interferon alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.