Anti-ITGAX/CD11c (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P20702
Gene Id	3687
Gene Symbols	ITGAX
Protein Name / Synonyms	ITGAX/CD11c (N-term)
Clonality	Monoclonal
Preparation	This ITGAX/CD11c antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human ITGAX/CD11c.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

Specificity

Other Names

ITGAX; CD11C; Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen=CD11c; Flags: Precursor

NCBI Accession #

NP_000878.2

Other Accession #

NP_000878.2

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

127829

Recommended Dilutions

WB: 1:100-500

ITGAX/CD11c Antibody (N-term) (Cat# 102-10242) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ITGAX/CD11c antibody detected the ITGAX/CD11c protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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