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Anti-ITGB2 (N-term) Antibody

Catalog #: 102-13678

Rabbit Anti-Human ITGB2 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P05107
Gene Id
3689
Gene Symbols
ITGB2
Protein Name / Synonyms
ITGB2 (N-term)
ClonalityPolyclonal
PreparationThis ITGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the N-terminal region of human ITGB2.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Research AreaAngiogenesis, Inflammation
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Specificity

Other Names
ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD_antigen=CD18; Flags: Precursor
NCBI Accession #
NP_000202.2;NP_001120963.1
Other Accession #
NP_000202.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
84782
Recommended Dilutions
WB: 1:1000
ITGB2 Antibody (N-term) (Cat# 102-13678) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ITGB2 antibody detected the ITGB2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.