Anti-ITPKA (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P23677
Gene Id	3706
Gene Symbols	ITPKA
Protein Name / Synonyms	ITPKA (C-term)
Clonality	Polyclonal
Preparation	This ITPKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of human ITPKA.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.

Specificity

Other Names

ITPKA; Inositol-trisphosphate 3-kinase A; Inositol 1,4,5-trisphosphate 3-kinase A

NCBI Accession #

NP_002211.1

Other Accession #

NP_002211

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

51009

Recommended Dilutions

WB: 1:1000

Western blot analysis of hITPKA-E360 (Cat# 102-17844) in K562 cell line and mouse lung tissue lysates (35ug/lane). ITPKA (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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