Anti-Kappa light chain Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P01834
Gene Symbols	IGKC
Protein Name / Synonyms	Kappa light chain
Clonality	Monoclonal
Preparation	This Kappa light chain monoclonal antibody is generated from mouse immunized with Kappa light chain recombinant protein.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two types of light chains designated as kappa and lambda (1). Light chain types are based on differences in the amino acid sequence in the constant region of the light chain. If a cell is unsuccessful in rearranging both of its kappa light chain genes, it then attempts to make a lambda light chain. If a cell successfully rearranges a lambda light chain gene, it will be a B cell that makes an immunoglobulin with a lambda light chain (2).

Specificity

Other Names

IGKC; Ig kappa chain C region

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

11609

Recommended Dilutions

WB: 1:100-1000; IHC: 1:10-50

	Kappa light chain Antibody western blot analysis in human serum protein (35ug/lane).This demonstrates the Kappa light chain antibody detected the Kappa light chain protein (arrow).
	Kappa light chain Antibody (Cat# 102-10205)immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Kappa light chain Antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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