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Anti-KCNA3 (Center) Antibody
Catalog #: 102-12605
Rabbit Anti-Human KCNA3 (Center) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | This KCNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human KCNA3. |
| Host Species | Rabbit |
| Accession Number | P22001 |
| Gene Id | 3738 |
| Gene Symbols | KCNA3 |
| Protein Name / Synonyms | KCNA3 (Center) |
| Clonality | Polyclonal |
| Preparation | This KCNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human KCNA3. |
| Isotype | IgG |
| Molecular Weight (kDa) | 63.842 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Predicted Reactivity
Mouse, Rat
Other Names
KCNA3; HGK5; Potassium voltage-gated channel subfamily A member 3; HLK3; HPCN3; Voltage-gated K(+) channel HuKIII; Voltage-gated potassium channel subunit Kv1.3
NCBI Accession #
NP_002223.3
Other Accession #
P15384; P16390; NP_002223.3
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Recommended Dilutions
WB: 1:1000
Storage/Stability
2-8°C (short-term); -20°C (long-term). 12 months from the date of shipment when stored properly.
Typical Data
Introduction
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.