RayBiotech

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ISO 13485:2016 cGMP

Anti-KCNE2 Antibody

Catalog #: 144-09859

KCNE2 Polyclonal Antibody

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse
Host SpeciesRabbit
Accession Number
Q9Y6J6
Gene Id
9992
Gene Symbols
KCNE2
Protein Name / Synonyms
KCNE2, ATFB4, LQT5, LQT6, MIRP1, potassium voltage-gated channel subfamily E member 2
ClonalityPolyclonal
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
14kDa
Observed MW
15kDa

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KCNE2 (NP_751951.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of U-251MG cells, using KCNE2 antibody (144-09859) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Western blot - KCNE2 antibody (144-09859)

Expiration:
12 months from the date of shipment when stored properly.