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Anti-KISS1R (Center) Antibody
Catalog #: 102-14639
Rabbit Anti-Human KISS1R (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q969F8 |
| Gene Id | 84634 |
| Gene Symbols | KISS1R |
| Protein Name / Synonyms | KISS1R (Center) |
| Clonality | Polyclonal |
| Preparation | This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R. |
| Concentration (lot specific) | 0.650 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
Specificity
Other Names
KISS1R;AXOR12; GPR54; KiSS-1 receptor; KiSS-1 receptor; G-protein coupled receptor 54; KiSS-1 receptor; G-protein coupled receptor OT7T175; KiSS-1 receptor; Hypogonadotropin-1; KiSS-1 receptor; Kisspeptins receptor; KiSS-1 receptor; Metastin receptor
NCBI Accession #
NP_115940.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42586
Recommended Dilutions
WB: 1:1000
 | KISS1R Antibody (Center) (Cat# 102-14639) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KISS1R antibody detected the KISS1R protein (arrow). |
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.