Anti-KRT80 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q6KB66
Gene Id	144501
Gene Symbols	KRT80
Protein Name / Synonyms	KRT80 (C-term)
Clonality	Polyclonal
Preparation	This KRT80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human KRT80.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.

Specificity

Other Names

KRT80; KB20; Keratin, type II cytoskeletal 80; Cytokeratin-80; Keratin-80; Type-II keratin Kb20

NCBI Accession #

NP_001074961.1;NP_872313.2

Other Accession #

NP_872313.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

50525

Recommended Dilutions

WB: 1:1000

KRT80 Antibody (C-term) (Cat# 102-10836) western blot analysis in NCI-H460,SK-BR-3 cell line lysates (35ug/lane).This demonstrates the KRT80 antibody detected the KRT80 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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