Anti-LDB3 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O75112
Gene Id	11155
Gene Symbols	LDB3
Protein Name / Synonyms	LDB3 (Center)
Clonality	Polyclonal
Preparation	This LDB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-262 amino acids from the Central region of human LDB3.
Concentration (lot specific)	0.300 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq].

Specificity

Other Names

LDB3; KIAA0613; ZASP; LIM domain-binding protein 3; Protein cypher; Z-band alternatively spliced PDZ-motif protein

NCBI Accession #

NP_001073583.1;NP_001073584.1;NP_001073585.1;NP_001165081.1;NP_001165082.1;NP_009009.1

Other Accession #

NP_001073584.1; NP_001073583.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

77135

Recommended Dilutions

WB: 1:1000

LDB3 Antibody (Center) (Cat# 102-13238) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the LDB3 antibody detected the LDB3 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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