Anti-LEF1 (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	Q9UJU2
Gene Id	51176
Gene Symbols	LEF1
Protein Name / Synonyms	LEF1 (Ascites)
Clonality	Monoclonal
Preparation	This LEF1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from human LEF1.
Recommended Applications	Western Blotting
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

LEF1; Lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha

NCBI Accession #

NP_001124185.1;NP_001124186.1;NP_001159591.1;NP_057353.1

Other Accession #

Q9QXN1; P27782; NP_057353.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

44201

Recommended Dilutions

WB: 1:500-8000

LEF1 Antibody (Cat# 102-10395) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LEF1 antibody detected the LEF1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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