Anti-LGALS3 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P17931
Gene Id	3958
Gene Symbols	LGALS3
Protein Name / Synonyms	LGALS3 (C-term)
Clonality	Monoclonal
Preparation	This LGALS3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human LGALS3.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.

Specificity

Other Names

LGALS3; MAC2; Galectin-3; 35 kDa lectin; Carbohydrate-binding protein 35; Galactose-specific lectin 3; Galactoside-binding protein; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen

NCBI Accession #

NP_002297.2

Other Accession #

NP_002297.2

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

26152

Recommended Dilutions

WB: 1:100-500; IHC: 1:10-50

	LGALS3 Antibody (C-term) (Cat# 102-10188) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the LGALS3 antibody detected the LGALS3 protein (arrow).
	LGALS3 Antibody (C-term) (Cat# 102-10188)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LGALS3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	LGALS3 Antibody (C-term) (Cat# 102-10188)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LGALS3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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