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Anti-MAPK11 (Center) Antibody
Catalog #: 102-17194
Rabbit Anti-MAPK11 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q15759 |
| Gene Id | 5600 |
| Gene Symbols | MAPK11 |
| Protein Name / Synonyms | MAPK11 (Center) |
| Clonality | Polyclonal |
| Preparation | This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-366 amino acids from the center region of human MAPK11. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | MAPK Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
MAPK11 is a Ser/Thr kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. It preferentially phosphorylates transcription factor ATF2. This protein is activated by phosphorylation on threonine and tyrosine by MKK6, and is inhibited by pyridinyl-imidazole related compounds. Highest expression levels are in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
Specificity
Other Names
MAPK11; PRKM11; SAPK2; SAPK2B; Mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; Stress-activated protein kinase 2b; p38-2
NCBI Accession #
NP_002742.3
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
41357
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-MAPK11 Pab (Cat# 102-17194) in mouse brain tissue lysate. MAPK11 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.