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Anti-Mapk8 (Center) Antibody
Catalog #: 102-21972
Rabbit Anti-Mouse Mapk8 (Center) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P45983|Q91Y86 and P45983|Q8QHK8|P49185|NP_057909.1|Q91Y86 |
| Protein Name / Synonyms | Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, Mapk8, Jnk1, Prkm8 |
| Clonality | Polyclonal |
| Clone | RB30269 |
| Isotype | IgG |
| Recommended Applications | Western Blotting |
| Research Area | MAPK Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Mapk8 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4 (HSF4) (By similarity).
Other Information
NCBI Accession #
NP_057909.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen Source
Mouse
Images
WB (1:1000)
Mouse Mapk8 Antibody (Center) (Cat. #102-21972) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the Mapk8 antibody detected the Mapk8 protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.