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Anti-MCAF2 (Center) Antibody
Catalog #: 102-10679
Rabbit Anti-MCAF2 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q5U623 |
| Gene Id | 80063 |
| Gene Symbols | ATF7IP2 |
| Protein Name / Synonyms | MCAF2 (Center) |
| Clonality | Polyclonal |
| Preparation | This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human MCAF2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
Specificity
Other Names
ATF7IP2; MCAF2; Activating transcription factor 7-interacting protein 2; MBD1-containing chromatin-associated factor 2
NCBI Accession #
NP_001243089.1;NP_079273.2
Other Accession #
NP_079273.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
75764
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | MCAF2 Antibody (Center) (Cat# 102-10679) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the MCAF2 antibody detected the MCAF2 protein (arrow). |
 | MCAF2 Antibody (Center) (Cat# 102-10679) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MCAF2 antibody detected the MCAF2 protein (arrow). |
 | MCAF2 Antibody (Center) (Cat# 102-10679) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCAF2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | MCAF2 Antibody (Center) (Cat# 102-10679) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.