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Anti-MCM2 (C-term) Antibody
Catalog #: 102-18250
Rabbit Anti-Human MCM2 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P49736 |
| Gene Id | 4171 |
| Gene Symbols | MCM2 |
| Protein Name / Synonyms | MCM2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This MCM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 649-677 amino acids from the C-terminal region of human MCM2. |
| Concentration (lot specific) | 0.450 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Specificity
Predicted Reactivity
Mouse, Xenopus
Other Names
MCM2; BM28; CCNL1; CDCL1; KIAA0030; DNA replication licensing factor MCM2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28
NCBI Accession #
NP_004517.2
Other Accession #
P55861; P97310
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
101896
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of MCM2 Antibody (C-term) (Cat# 102-18250) in HL-60 cell line lysates (35ug/lane). MCM2 (arrow) was detected using the purified Pab. |
 | MCM2 Antibody (C-term) (Cat# 102-18250) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCM2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.