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Anti-MCM3 (N-term) Antibody
Catalog #: 102-12264
Rabbit Anti-Human MCM3 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P25205 |
| Gene Id | 4172 |
| Gene Symbols | MCM3 |
| Protein Name / Synonyms | MCM3 (N-term) |
| Clonality | Polyclonal |
| Preparation | This MCM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human MCM3. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
MCM3; DNA replication licensing factor MCM3; DNA polymerase alpha holoenzyme-associated protein P1; P1-MCM3; RLF subunit beta; p102
NCBI Accession #
NP_001257401.1;NP_002379.3
Other Accession #
P25206; A4FUD9; NP_002379.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
90981
Recommended Dilutions
WB: 1:1000
 | MCM3 Antibody (N-term) (Cat# 102-12264) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the MCM3 antibody detected the MCM3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.