| Size | 20 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | This product recognizes the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer. |
| Host Species | Mouse |
| Protein Name / Synonyms | MDM2 |
| Concentration (lot specific) | IgG concentration 1.0 mg/ml |
| Recommended Applications | Immunohistology - Frozen, Immunohistology - Paraffin, Immunohistology - Resin |
| Research Area | Cancer, p53 Signaling, DNA Damage |
| Shipping Type | Blue ice |
| Storage | -20°C |
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Anti-MDM2 Antibody
Anti-MDM2 Antibody