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Anti-MDM4 (Center) Antibody
Catalog #: 102-12197
Rabbit Anti-Human MDM4 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O15151 |
| Gene Id | 4194 |
| Gene Symbols | MDM4 |
| Protein Name / Synonyms | MDM4 (Center) |
| Clonality | Polyclonal |
| Preparation | This MDM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human MDM4. |
| Concentration (lot specific) | 0.320 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease, Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene.
Specificity
Other Names
MDM4; MDMX; Protein Mdm4; Protein Mdmx; Double minute 4 protein; Mdm2-like p53-binding protein; p53-binding protein Mdm4
NCBI Accession #
NP_001191100.1;NP_001191101.1;NP_001265445.1;NP_001265446.1;NP_001265447.1;NP_001265448.1;NP_002384.2
Other Accession #
NP_002384.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
54864
Recommended Dilutions
WB: 1:1000
 | MDM4 Antibody (Center) (Cat# 102-12197) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MDM4 antibody detected the MDM4 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.