Anti-ME2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P23368
Gene Id	4200
Gene Symbols	ME2
Protein Name / Synonyms	ME2 (C-term)
Clonality	Polyclonal
Preparation	This ME2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human ME2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	IHC-P, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq].

Specificity

Other Names

ME2; NAD-dependent malic enzyme, mitochondrial; Malic enzyme 2

NCBI Accession #

NP_001161807.1;NP_002387.1

Other Accession #

NP_002387.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

65444

Recommended Dilutions

IHC: 1:10-50; WB: 1:1000

	ME2 Antibody (C-term) (Cat# 102-11655)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ME2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	ME2 Antibody (C-term) (Cat# 102-11655) western blot analysis in mouse NIH-3T3,Neuro-2a cell line lysates (35ug/lane).This demonstrates the ME2 antibody detected the ME2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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