Anti-MED7 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O43513
Gene Id	9443
Gene Symbols	MED7
Protein Name / Synonyms	MED7 (Center)
Clonality	Polyclonal
Preparation	This MED7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the Central region of human MED7.
Concentration (lot specific)	0.280 mg/ml
Recommended Applications	Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Specificity

Predicted Reactivity

Mouse, Bovine, Pig

Other Names

MED7; ARC34; CRSP9; Mediator of RNA polymerase II transcription subunit 7; Activator-recruited cofactor 34 kDa component; Cofactor required for Sp1 transcriptional activation subunit 9; Mediator complex subunit 7; RNA polymerase transcriptional regulation mediator subunit 7 homolog; Transcriptional coactivator CRSP33

NCBI Accession #

NP_001094286.1;NP_004261.1

Other Accession #

Q2F7Z4; Q9CZB6; Q3T123; NP_004261

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

27245

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	MED7 Antibody (Center) (Cat# 102-11334) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the MED7 antibody detected the MED7 protein (arrow).
	MED7 Antibody (Center) (Cat# 102-11334) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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