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Anti-MGMT Antibody
Catalog #: 102-10442
Mouse Anti-Human MGMT Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P16455 |
| Gene Id | 4255 |
| Gene Symbols | MGMT |
| Protein Name / Synonyms | MGMT |
| Clonality | Monoclonal |
| Preparation | Purified His-tagged MGMT protein was used to produced this monoclonal antibody. |
| Concentration (lot specific) | 0.270 mg/ml |
| Recommended Applications | Western Blotting, IF, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Specificity
Other Names
MGMT;Methylated-DNA--protein-cysteine methyltransferase; Methylated-DNA--protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; Methylated-DNA--protein-cysteine methyltransferase; O-6-methylguanine-DNA-alkyltransferase
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
21646
Recommended Dilutions
WB: 1:1000
 | MGMT Antibody(Cat# 102-10442) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the MGMT antibody detected the MGMT protein (arrow). |
Antigen Source
Human
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.