Anti-MLF1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P58340
Gene Id	4291
Gene Symbols	MLF1
Protein Name / Synonyms	Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, MLF1
Clonality	Polyclonal
Clone	RB18643
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, FC, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Other Information

NCBI Accession #

NP_001123628.1;NP_001123629.1;NP_001182361.1;NP_001182362.1;NP_001182363.1;NP_071888.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

30627

Antigen Source

Human

Images

WB (1:1000)

Western blot analysis of MLF1 (arrow) using rabbit polyclonal MLF1 Antibody (C-term) (Cat. #102-27083). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MLF1 gene.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products