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Anti-MMP12 Antibody
Catalog #: 144-64791
MMP12 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P39900 |
| Gene Id | 4321 |
| Gene Symbols | MMP12 |
| Protein Name / Synonyms | MMP12, HME, ME, MME, MMP-12, macrophage metalloelastase |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, pH7.3 |
| Recommended Applications | Western Blotting, IHC, IF |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11.
Dilutions
WB 1:500 - 1:1000; IHC 1:50 - 1:100; IF 1:20 - 1:50
Format
Calculated MW
54kDa
Observed MW
51kDa
Immunogen
A synthetic peptide of human MMP12
Modification
Unmodified
Storage
Store at 4?. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.