Anti-MMP20 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O60882
Gene Id	9313
Gene Symbols	MMP20
Protein Name / Synonyms	MMP20 (C-term)
Clonality	Polyclonal
Preparation	This MMP20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human MMP20.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes that localizes to chromosome 11q22.3.

Specificity

Predicted Reactivity

Bovine

Other Names

MMP20; Matrix metalloproteinase-20; Enamel metalloproteinase; Enamelysin

NCBI Accession #

NP_004762.2

Other Accession #

O18767; NP_004762.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

54387

Recommended Dilutions

WB: 1:1000

MMP20 Antibody (C-term) (Cat# 102-12206) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MMP20 antibody detected the MMP20 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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