Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.

WB 1:500 - 1:2000; IHC 1:50 - 1:100; IF 1:50 - 1:100

Recombinant fusion protein containing a sequence corresponding to amino acids 949-1228 of human MMRN1 (NP_031377.2).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.