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ISO 13485:2016 cGMP

Anti-Monkey HCAM Antibody CD44

Catalog #: 188-10043

Mouse anti-Human/Baboon/Green Monkey HCAM Antibody CD44

Product Description

Specifications

Size20 µg, 100 µg
Estimated Lead Time1-2 weeks
SpeciesHuman
Specificity
Other species not known
Host SpeciesMouse
Accession Number
P16070
Gene Id
960
Gene Symbols
CD44,LHR,MDU2,MDU3,MIC4
Protein Name / Synonyms
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Immunogen
Stimulated human leukocytes were used as the immunogen for this CD44 / HCAM antibody.
IsotypeKappa, IgG2a
Purity
Protein G affinity chromatography
Concentration (lot specific)
0.2 mg/ml in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Recommended Applications
ELISA: order BSA-free format for coating
FACS: 0.5-1ug/million cells
IF: 0.5-1ug/ml
Western Blotting: 0.5-1ug/ml
IHC (FFPE): 0.5-1ug/ml for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Domain / Region / TerminusCell surface
Research AreaInflammation
Shipping TypeBlue ice
Storage≤-20°C

Description

Description

This antibody recognizes a cell surface glycoprotein of 80-95kDa, called CD44, or HCAM, on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95kDa or hematopoietic variant (CD44-s). Higher molecular weight isoforms are described in epithelial cells (CD44-v), which are believed to function in intercellular adhesion and stromal binding. HCAM antibody immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

Storage

Store the HCAM antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.