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Anti-Monkey/Rabbit PECAM-1 Antibody, PE
Catalog #: 188-10623-PE
Mouse anti-Human/Cynomolgus Monkey/Rabbit PECAM-1 Antibody [PE Conjugated]
Product Description
Specifications
| Size | 100 tests |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Does not react with rat. Other species not tested. |
| Host Species | Mouse |
| Accession Number | P16284 |
| Gene Id | 5175 |
| Gene Symbols | PECAM1 |
| Protein Name / Synonyms | Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31) |
| Immunogen | Membrane preparation of a spleen from a patient with hairy cell leukemia was used as the immunogen for the PECAM-1 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 500 ul at 0.1 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Flow Cytometry: 5ul per test per one million cells in 0.1ml or 5ul per 100ul of whole blood Immunofluorescence: 1:50-1:100 for 30 min at RT |
| Domain / Region / Terminus | Cell surface and cytoplasmic |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | 2-8°C |
Description
Description
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Storage
Store the PECAM-1 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Expiration:
12 months from the date of shipment when stored properly.