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Anti-Mouse CD117 Antibody, Biotinylated
Catalog #: 135-01070
Mouse CD117 Biotinylated Antibody [clone: 2B8], monoclonal Rat IgG2b. Validated for flow cytometry.
Product Description
Specifications
| Size | 100 µg, 500 µg |
| Estimated Lead Time | 3-5 business days |
| Species | Mouse |
| Host Species | Rat |
| Clonality | Monoclonal |
| Clone | 2B8 |
| Conjugation | Biotin |
| Preparation | The antibody was purified by affinity chromatography, and conjugated with biotin. |
| Isotype | IgG2b |
| Format | Liquid |
| Concentration (lot specific) | 0.5 mg/mL |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
CD117 is a 145 kD transmembrane tyrosine-kinase receptor that binds the c-Kit ligand. CD117 is expressed in hematopoietic stem cells, mast cells, and acute myeloid leukemia (AML) cells. The interaction of CD117 with its ligand is important for the growth of hematopoietic stem cells.