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Anti-Mouse CD117 Antibody, Purified
Catalog #: 135-00070
Mouse CD117 Antibody [clone: 2B8], monoclonal Rat IgG2b. Validated for flow cytometry.
Product Description
Specifications
| Size | 100 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Mouse |
| Host Species | Rat |
| Clonality | Monoclonal |
| Clone | 2B8 |
| Preparation | The antibody was purified by affinity chromatography. |
| Isotype | IgG2b |
| Format | Lyophilized |
| Concentration (lot specific) | Lyophilized |
| Buffers | PBS, pH 7.2-7.4; Carrier-free |
| Recommended Applications | Flow Cytometry |
| Reconstitution | Reconstitute in desired amount of PBS. |
| Research Area | Cardiovascular Disease |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
- Carrier free
- Endotoxin-free
Description
CD117 is a 145 kD transmembrane tyrosine-kinase receptor that binds the c-Kit ligand. CD117 is expressed in hematopoietic stem cells, mast cells, and acute myeloid leukemia (AML) cells. The interaction of CD117 with its ligand is important for the growth of hematopoietic stem cells.