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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | O88508 |
| Gene Id | 13435 |
| Gene Symbols | DNMT3A K44me2 |
| Protein Name / Synonyms | Dnmt3a, MmuIIIA, DNMT3A2, M.HsaIIIA, TBRS, DNA methyltransferase 3A |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | IF |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Dilutions
IF 1:50 - 1:200
Format
Calculated MW
77kDa/101kDa
Observed MW
Immunogen
A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.