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ISO 13485:2016 cGMP

Anti-Mouse GUCA2B Antibody

Catalog #: 144-08390

GUCA2B Polyclonal Antibody

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesMouse
Host SpeciesRabbit
Accession Number
Q16661
Gene Id
2981
Gene Symbols
GUCA2B
Protein Name / Synonyms
GUCA2B, GCAP-II, UGN, guanylate cyclase activator 2B
ClonalityPolyclonal
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
12kDa
Observed MW
12kDa

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GUCA2B (NP_009033.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of mouse small intestine, using GUCA2B antibody (144-08390) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Western blot - GUCA2B antibody (144-08390)

Expiration:
12 months from the date of shipment when stored properly.