RayBiotech

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Anti-Mouse Hes1 (C-term) Antibody

Catalog #: 102-24200

Rabbit Anti-Mouse Hes1 (C-term) Antibody, 400 µl

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesMouse
Host SpeciesRabbit
Accession Number
Q14469|Q04666|P35428
Gene Id
15205
Gene Symbols
Hes1
Protein Name / Synonyms
Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1
ClonalityPolyclonal
CloneRB51068
IsotypeKappa, Rabbit
Recommended ApplicationsWestern Blotting
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).

Other Information

Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
29749
Antigen Source
Human

Images

WB (1:500)

Western blot analysis of lysate from mouse kidney tissue lysate, using Hes1 Antibody (C-term)(Cat. #102-24200). 102-24200 was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

WB

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.